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Synthesis of Pleuromutilin | Journal of the American Chemical Society
Synthesis of Pleuromutilin | Journal of the American Chemical Society

A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism | Scientific Reports
A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism | Scientific Reports

Discovery of a Potent Adenine–Benzyltriazolo–Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA | Journal of Medicinal Chemistry
Discovery of a Potent Adenine–Benzyltriazolo–Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA | Journal of Medicinal Chemistry

Antibacterial properties and clinical potential of pleuromutilins - Natural Product Reports (RSC Publishing) DOI:10.1039/C8NP00042E
Antibacterial properties and clinical potential of pleuromutilins - Natural Product Reports (RSC Publishing) DOI:10.1039/C8NP00042E

Full article: A click chemistry approach to pleuromutilin derivatives, evaluation of anti-MRSA activity and elucidation of binding mode by surface plasmon resonance and molecular docking
Full article: A click chemistry approach to pleuromutilin derivatives, evaluation of anti-MRSA activity and elucidation of binding mode by surface plasmon resonance and molecular docking

Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity | PNAS
Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity | PNAS

Nathan Letts, PhD 🇺🇦🇺🇦🇺🇦 on Twitter: "1st #Antibiotic With New MOA Approved by the @US_FDA in Almost 20 Years Lemafulin (Xenleta, C-3781) is a pleuromutilin antibiotic that binds to the 50S ribosome
Nathan Letts, PhD 🇺🇦🇺🇦🇺🇦 on Twitter: "1st #Antibiotic With New MOA Approved by the @US_FDA in Almost 20 Years Lemafulin (Xenleta, C-3781) is a pleuromutilin antibiotic that binds to the 50S ribosome

Ribosomal binding site of the pleuromutilin antibiotics. (A) Secondary... | Download Scientific Diagram
Ribosomal binding site of the pleuromutilin antibiotics. (A) Secondary... | Download Scientific Diagram

Total synthesis of structurally diverse pleuromutilin antibiotics | Nature Chemistry
Total synthesis of structurally diverse pleuromutilin antibiotics | Nature Chemistry

Design, synthesis, and biological activity evaluation of a series of pleuromutilin derivatives with novel C14 side chains - ScienceDirect
Design, synthesis, and biological activity evaluation of a series of pleuromutilin derivatives with novel C14 side chains - ScienceDirect

Daptomycin: Mechanism of Action and Bacterial Resistance | Semantic Scholar
Daptomycin: Mechanism of Action and Bacterial Resistance | Semantic Scholar

Semi‐synthesis, antibacterial activity, and molecular docking study of novel pleuromutilin derivatives bearing cinnamic acids moieties - Deng - 2019 - Archiv der Pharmazie - Wiley Online Library
Semi‐synthesis, antibacterial activity, and molecular docking study of novel pleuromutilin derivatives bearing cinnamic acids moieties - Deng - 2019 - Archiv der Pharmazie - Wiley Online Library

PDF] Pleuromutilins: Potent Drugs for Resistant Bugs-Mode of Action and Resistance. | Semantic Scholar
PDF] Pleuromutilins: Potent Drugs for Resistant Bugs-Mode of Action and Resistance. | Semantic Scholar

Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Acquired Bacterial Pneumonia | SpringerLink
Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Acquired Bacterial Pneumonia | SpringerLink

Molecules | Free Full-Text | Discovery of Novel Pleuromutilin Derivatives as Potent Antibacterial Agents for the Treatment of MRSA Infection
Molecules | Free Full-Text | Discovery of Novel Pleuromutilin Derivatives as Potent Antibacterial Agents for the Treatment of MRSA Infection

Lefamulin - Microregistrar.com
Lefamulin - Microregistrar.com

Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives | Nature Communications
Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives | Nature Communications

SYNTHESIS AND IN VITRO ANTIBACTERIAL ACTIVITY OF FOUR NOVEL PLEUROMUTILIN DERIVATIVES
SYNTHESIS AND IN VITRO ANTIBACTERIAL ACTIVITY OF FOUR NOVEL PLEUROMUTILIN DERIVATIVES

Clinical use of lefamulin: A first‐in‐class semisynthetic pleuromutilin antibiotic - Covvey - 2022 - Journal of Internal Medicine - Wiley Online Library
Clinical use of lefamulin: A first‐in‐class semisynthetic pleuromutilin antibiotic - Covvey - 2022 - Journal of Internal Medicine - Wiley Online Library

Full article: Design, synthesis and antibacterial activities of pleuromutilin derivatives
Full article: Design, synthesis and antibacterial activities of pleuromutilin derivatives

Pleuromutilin and its Derivatives: Promising Novel Anti-Infective Agents | Bentham Science
Pleuromutilin and its Derivatives: Promising Novel Anti-Infective Agents | Bentham Science

Lefamulin - an overview | ScienceDirect Topics
Lefamulin - an overview | ScienceDirect Topics

Pleuromutilin - Wikipedia
Pleuromutilin - Wikipedia

Pharmaceutics | Free Full-Text | The Very First Modification of Pleuromutilin and Lefamulin by Photoinitiated Radical Addition Reactions—Synthesis and Antibacterial Studies
Pharmaceutics | Free Full-Text | The Very First Modification of Pleuromutilin and Lefamulin by Photoinitiated Radical Addition Reactions—Synthesis and Antibacterial Studies